Greg and I got eMacs at work last week. Here are the only annoying things that have come up, as far as I can recall.

Is it at all possible to select a dropdown item in a web form on Safari using only the keyboard?
Can you mount SMB network drives automatically when you login? (I’ve seen this and this, and have tried that with no success)
Does Apple make some kind of iCal corporate server? Something akin to Exchange’s calendar, that is?
Is it possible to print to an SMB network printer? (a DeskJet 3820)

Those are my only OS X questions after a week of using it at the Zipcar office. Considering it’s otherwise 100% Windows at the office (including the Exchange server), I’d say the switch was pretty smooth. We have Active Directory authentication going on and everything. We had to give up the following apps:

• MPLAB IDE and PIC C compiler, for embedded systems programming
  
• TOAD SQL monitor, which isn’t that great anyway. But I still haven’t found an excellent SQL monitor for the Mac. Or for any platform, really.
  
• Exchange calendar features (iCal is cooler, but it won’t sync with Exchange afaik)
  
• Oracle Enterprise Management stuff. It runs in Java but … you know how Oracle is. Oracle’s OS X progress seems to have come to a halt a year or so ago.

That’s it, I think. I could probably do ALL of these things with Virtual PC, which Microsoft will supposedly update soon. Granted, that’s half the software I use for my job, but it’s the less important half. Safari, ssh, a good text editor, and CVS is the other half.

Meanwhile, others in the office are wowed by everything from Exposé to the eject button on the keyboard.